Speech-induced Aphasic Seizures in Epilepsy Caused by LGI1 Mutation
نویسندگان
چکیده
منابع مشابه
A de novo LGI1 mutation causing idiopathic partial epilepsy with telephone-induced seizures.
R. Michelucci, MD O. Mecarelli, MD G. Bovo, MSc F. Bisulli, MD S. Testoni, MD P. Striano, MD S. Striano, MD P. Tinuper, MD C. Nobile, PhD A DE NOVO LGI1 MUTATION CAUSING IDIOPATHIC PARTIAL EPILEPSY WITH TELEPHONE-INDUCED SEIZURES Telephone-induced seizures have recently been described as a distinct form of idiopathic reflex epilepsy in which seizures are repeatedly and exclusively triggered by ...
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Limbic encephalitis (LE), once thought to be a rare paraneoplastic phenomenon, is increasingly diagnosed in patients without malignancy. Autoimmune LE has emerged as a distinct clinical entity. Autoantibodies to neuronal cell surface proteins have been described and may now be tested for. This has led to an exponential increase in the number of cases being reported. The most recently implicated...
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Leucin-rich, glioma inactivated 1 (LGI1) is a secreted protein linked to human seizures of both genetic and autoimmune aetiology. Mutations in the LGI1 gene are responsible for autosomal dominant temporal lobe epilepsy with auditory features, whereas LGI1 autoantibodies are involved in limbic encephalitis, an acquired epileptic disorder associated with cognitive impairment. We and others previo...
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PURPOSE A new leucine-rich glioma-inactivated 1 gene (LGI1) mutation inducing an amino acid sequence substitution was found in a Korean family with autosomal dominant lateral temporal lobe epilepsy (ADLTE). We report the clinical features and characteristics of this newly identified LGI1 mutation. METHODS Clinical data were collected from a large ADLTE family. All exons and flanking regions o...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2005
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.1528-1167.2005.47104.x